| Reaction Details |
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 | Report a problem with these data |
| Target | 26S proteasome non-ATPase regulatory subunit 14 |
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| Ligand | BDBM224013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | 2800±350 nM |
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| Citation |  Deshaies, RJ; Li, J; Cohen, S; Perez, C; Ma, Y Inhibitors of RPN11 US Patent US10005735 Publication Date 6/26/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| 26S proteasome non-ATPase regulatory subunit 14 |
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| Name: | 26S proteasome non-ATPase regulatory subunit 14 |
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| Synonyms: | 26S Proteasome regulatory subunit Rpn11 (Rpn11) | POH1 | PSDE_HUMAN | PSMD14 | PSMD14 protein |
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| Type: | Protein |
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| Mol. Mass.: | 34576.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00487 |
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| Residue: | 310 |
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| Sequence: | MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH
NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL
AAMLDTVVFK
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| BDBM224013 |
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| n/a |
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| Name | BDBM224013 |
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| Synonyms: | 8-Mercaptoquinoline (8TQ) | US10005735, Example 8TQ |
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| Type | Small organic molecule |
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| Emp. Form. | C9H7NS |
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| Mol. Mass. | 161.224 |
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| SMILES | Sc1cccc2cccnc12 |
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| Structure | 
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