| Reaction Details |
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 | Report a problem with these data |
| Target | AMSH-like protease |
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| Ligand | BDBM401006 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | 500±n/a nM |
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| Citation |  Deshaies, RJ; Li, J; Cohen, S; Perez, C; Ma, Y Inhibitors of RPN11 US Patent US10005735 Publication Date 6/26/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| AMSH-like protease |
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| Name: | AMSH-like protease |
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| Synonyms: | AMSH-LP | AMSHLP | KIAA1373 | STALP_HUMAN | STAM-binding protein-like 1 (AMSH) | STAMBPL1 |
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| Type: | Protein |
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| Mol. Mass.: | 49789.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96FJ0 |
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| Residue: | 436 |
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| Sequence: | MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMER
MASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDE
LKNDLLKKYNVEYQEYLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFF
EDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYAS
HSPPVNRALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGK
LTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVD
LHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSIC
KHVLVKDIKIIVLDLR
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|
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| BDBM401006 |
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| n/a |
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| Name | BDBM401006 |
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| Synonyms: | US10005735, Compound 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N3OS |
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| Mol. Mass. | 295.359 |
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| SMILES | Sc1cccc2cc(cnc12)C(=O)NCc1ccncc1 |
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| Structure | 
|
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