| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 26S proteasome non-ATPase regulatory subunit 14 |
|---|
| Ligand | BDBM401023 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biochemical Assay |
|---|
| IC50 | 800±n/a nM |
|---|
| Citation |  Deshaies, RJ; Li, J; Cohen, S; Perez, C; Ma, Y Inhibitors of RPN11 US Patent US10005735 Publication Date 6/26/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 26S proteasome non-ATPase regulatory subunit 14 |
|---|
| Name: | 26S proteasome non-ATPase regulatory subunit 14 |
|---|
| Synonyms: | 26S Proteasome regulatory subunit Rpn11 (Rpn11) | POH1 | PSDE_HUMAN | PSMD14 | PSMD14 protein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 34576.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O00487 |
|---|
| Residue: | 310 |
|---|
| Sequence: | MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH
NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL
AAMLDTVVFK
|
|
|
|---|
| BDBM401023 |
|---|
| n/a |
|---|
| Name | BDBM401023 |
|---|
| Synonyms: | US10005735, Compound 21 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21N3O2S |
|---|
| Mol. Mass. | 379.475 |
|---|
| SMILES | Sc1cccc2cc(cnc12)C(=O)NCc1ccc(cc1)N1CCOCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
