| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C delta type |
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| Ligand | BDBM35157 |
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| Substrate/Competitor | PKC Peptide Substrate |
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| Meas. Tech. | PKC IMAP Kinase Assay |
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| IC50 | 2000±n/a nM |
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| Citation |  Tumey, LN; Bhagirath, N; Brennan, A; Brooijmans, N; Lee, J; Yang, X; Boschelli, DH 5-Vinyl-3-pyridinecarbonitrile inhibitors of PKCtheta: optimization of enzymatic and functional activity. Bioorg Med Chem17:7933-48 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein kinase C delta type |
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| Name: | Protein kinase C delta type |
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| Synonyms: | KPCD_HUMAN | PKC delta | PKCD | PRKCD | Protein Kinase C- delta | Protein kinase C, PKC; classical/novel | nPKC-delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 77516.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
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| Residue: | 676 |
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| Sequence: | MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR
RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSF
GKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVL
LDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIH
PFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAF
AGFSFVNPKFEHLLED
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| BDBM35157 |
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| PKC Peptide Substrate |
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| Name: | PKC Peptide Substrate |
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| Synonyms: | n/a |
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| Type: | Fluorescent peptide |
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| Mol. Mass.: | 2051.95 |
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| Organism: | n/a |
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| Description: | n/a |
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| Residue: | 17 |
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| Sequence: | |
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