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TargetProcathepsin L
LigandBDBM36334
Substrate/CompetitorFluorogenic Substrate
Meas. Tech.Enzyme kinetic assay
pH6.25±0
Temperature298.15±0 K
IC50 2.98e+3±n/a nM
Citation Lee, J; Bogyo, M Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. ACS Chem Biol5:233-43 (2010) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Procathepsin L
Name:Procathepsin L
Synonyms:CATL1_MOUSE | Cathepsin L | Ctsl | Ctsl1 | Q543M3
Type:PROTEIN
Mol. Mass.:37548.98
Organism:Mus musculus
Description:n/a
Residue:334
Sequence:
MNLLLLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQ
LHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLKIPKSVDW
REKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNG
GLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKAVA
TVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKN
SWGSEWGMEGYIKIAKDRDNHCGLATAASYPVVN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM36334
Fluorogenic Substrate
Name:Fluorogenic Substrate
Synonyms:n/a
Type:Peptide
Mol. Mass.:1645.93
Organism:n/a
Description:n/a
Residue:15
Sequence:
Cbz-Phe-Arg-AMC (Bachem)