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TargetCaspase-3
LigandBDBM36332
Substrate/CompetitorCaspase-3 (7) Fluorogenic Substrate
Meas. Tech.Enzyme kinetic assay
pH7.4±0
Temperature298.15±0 K
IC50 8.90e+5±n/a nM
Citation Lee, J; Bogyo, M Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. ACS Chem Biol5:233-43 (2010) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Caspase-3
Name:Caspase-3
Synonyms:CASP3_MOUSE | Casp3 | Cpp32
Type:PROTEIN
Mol. Mass.:31476.45
Organism:Mus musculus
Description:EBI_101489
Residue:277
Sequence:
MENNKTSVDSKSINNFEVKTIHGSKSVDSGIYLDSSYKMDYPEMGICIIINNKNFHKSTG
MSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVSKEDHSKRSSFVCVILS
HGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDE
EMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVN
RKVATEFESFSLDSTFHAKKQIPCIVSMLTKELYFYH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM36332
Caspase-3 (7) Fluorogenic Substrate
Name:Caspase-3 (7) Fluorogenic Substrate
Synonyms:n/a
Type:n/a
Mol. Mass.:1477.75
Organism:n/a
Description:AFC = 7-Amino-4-trifluoromethylcoumarin
Residue:16
Sequence:
Ac-Asp-Glu-Val-Asp-AFC