| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase CTX-M-1 |
|---|
| Ligand | BDBM36437 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Beta-lactamase CTX-M Inhibition Assay |
|---|
| pH | 7±0 |
|---|
| Ki | >10000000±0.0 nM |
|---|
| Citation |  Chen, Y; Shoichet, BK Molecular docking and ligand specificity in fragment-based inhibitor discovery. Nat Chem Biol5:358-64 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Beta-lactamase CTX-M-1 |
|---|
| Name: | Beta-lactamase CTX-M-1 |
|---|
| Synonyms: | BLC1_ECOLX | Beta-lactamase (CTX-M) | bla | class A beta-lactamase CTX-M-1 | men1 |
|---|
| Type: | Protien |
|---|
| Mol. Mass.: | 31251.38 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | Q7AVW6 |
|---|
| Residue: | 291 |
|---|
| Sequence: | MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQSGGRLGVALINTADNSQ
ILYRADERFAMCSTSKVMAVAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTM
SLAELSAAALQYSDNVAMNKLISHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDP
RDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGS
GDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTNGL
|
|
|
|---|
| BDBM36437 |
|---|
| n/a |
|---|
| Name | BDBM36437 |
|---|
| Synonyms: | CID7357365 | ZINC04784270, 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H9N6O |
|---|
| Mol. Mass. | 193.1865 |
|---|
| SMILES | CCc1c(C)[nH]n(-c2nn[n-]n2)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
