| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase CTX-M-1 |
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| Ligand | BDBM36439 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Beta-lactamase CTX-M Inhibition Assay |
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| pH | 7±0 |
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| Ki | 3100000±0.0 nM |
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| Citation |  Chen, Y; Shoichet, BK Molecular docking and ligand specificity in fragment-based inhibitor discovery. Nat Chem Biol5:358-64 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase CTX-M-1 |
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| Name: | Beta-lactamase CTX-M-1 |
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| Synonyms: | BLC1_ECOLX | Beta-lactamase (CTX-M) | bla | class A beta-lactamase CTX-M-1 | men1 |
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| Type: | Protien |
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| Mol. Mass.: | 31251.38 |
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| Organism: | Escherichia coli |
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| Description: | Q7AVW6 |
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| Residue: | 291 |
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| Sequence: | MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQSGGRLGVALINTADNSQ
ILYRADERFAMCSTSKVMAVAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTM
SLAELSAAALQYSDNVAMNKLISHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDP
RDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGS
GDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTNGL
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|
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| BDBM36439 |
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| n/a |
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| Name | BDBM36439 |
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| Synonyms: | CID7100106 | ZINC04105014, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8F2NO3 |
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| Mol. Mass. | 240.1835 |
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| SMILES | [O-]C(=O)[C@H]1C[C@H]1C(=O)Nc1cc(F)ccc1F |
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| Structure | 
|
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