| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM36447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Beta-lactamase AmpC Inhibition Assay |
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| pH | 7±0 |
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| Ki | 1500000±0.0 nM |
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| Citation |  Chen, Y; Shoichet, BK Molecular docking and ligand specificity in fragment-based inhibitor discovery. Nat Chem Biol5:358-64 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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|
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| BDBM36447 |
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| n/a |
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| Name | BDBM36447 |
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| Synonyms: | CID 7263523 | ZINC04511491, 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11N6OS |
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| Mol. Mass. | 287.321 |
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| SMILES | O=c1n(Cc2nn[n-]n2)cnc2sc3CCCCc3c12 |
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| Structure | 
|
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