| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor |
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| Ligand | BDBM40499 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation |
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| EC50 | 12796.55±n/a nM |
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| Citation |  PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Estrogen receptor |
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| Name: | Estrogen receptor |
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| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 |
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| Type: | Protein |
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| Mol. Mass.: | 66230.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03372 |
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| Residue: | 595 |
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| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
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| BDBM40499 |
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| n/a |
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| Name | BDBM40499 |
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| Synonyms: | MLS000054352 | SMR000066061 | [1-(4-chlorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [1-(4-chlorophenyl)-3-methyl-thieno[2,3-c]pyrazol-5-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone | [1-(4-chlorophenyl)-3-methyl-thieno[2,3-c]pyrazol-5-yl]-[4-(2-pyridyl)piperazino]methanone | [1-(4-chlorophenyl)-3-methylthieno[2,3-c]pyrazol-5-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone | cid_2997981 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20ClN5OS |
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| Mol. Mass. | 437.945 |
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| SMILES | Cc1nn(-c2ccc(Cl)cc2)c2sc(cc12)C(=O)N1CCN(CC1)c1ccccn1 |
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| Structure | 
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