| Reaction Details |
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 | Report a problem with these data |
| Target | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
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| Ligand | BDBM43867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competition Assay |
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| pH | 7.5±0 |
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| Temperature | 273.15±n/a K |
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| Km | 300±0 nM |
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| Citation |  Peluso, S; de L Ufret, M; O'Reilly, MK; Imperiali, B Neoglycopeptides as inhibitors of oligosaccharyl transferase: insight into negotiating product inhibition. Chem Biol9:1323-8 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
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| Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
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| Synonyms: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | NLT1 | OST1 | OST1_YEAST | Oligosaccharyl transferase (OT) | Oligosaccharyl transferase subunit alpha |
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| Type: | Protein |
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| Mol. Mass.: | 54057.61 |
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| Organism: | Saccharomyces cerevisiae (Baker's yeast) |
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| Description: | P41543 |
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| Residue: | 476 |
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| Sequence: | MRQVWFSWIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIAS
EPATEYFTAFESGIFSKVSFFSAYFTNEATFLNSQLLANSTTAPGDDGESEIRYGIIQFP
NAISPQEEVSLVIKSFYNTVGIPYPEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGS
SSFEEYHPPNDESLLGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDI
WLSHWASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDMLLPEGAT
DHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNKLSDFLHVSSGSDEKFV
ASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDSPVPFTNVSIETQKSYFDLNKGHVKLT
FSYRNLISQVANGQVLIKYDYPKSSFFKKPLSIACYIFTALMGVFVLKTLNMNVTN
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| BDBM43867 |
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| n/a |
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| Name | BDBM43867 |
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| Synonyms: | Glycopeptide, 1 |
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| Type | Peptide |
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| Emp. Form. | C37H51N9O12 |
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| Mol. Mass. | 813.8539 |
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| SMILES | CC(C)C(NC(=O)C(NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)c1ccccc1)[C@H](C)O)C(=O)NC([C@H](C)O)C(=O)N[C@@H](Cc1ccc(cc1)N(=O)=O)C(N)=O |r| |
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| Structure | 
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