| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
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| Ligand | BDBM47546 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 5219±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
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| BDBM47546 |
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| n/a |
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| Name | BDBM47546 |
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| Synonyms: | 2-[[(E)-1-oxo-3-thiophen-2-ylprop-2-enyl]amino]-4-phenyl-3-thiophenecarboxylic acid | 4-phenyl-2-[[(E)-3-(2-thienyl)acryloyl]amino]-3-thenoic acid | 4-phenyl-2-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]thiophene-3-carboxylic acid | MLS000773385 | SMR000364116 | cid_1177253 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C18H13NO3S2 |
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| Mol. Mass. | 355.431 |
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| SMILES | OC(=O)c1c(NC(=O)\C=C\c2cccs2)scc1-c1ccccc1 |
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| Structure | 
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|---|
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