| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
|---|
| Ligand | BDBM47876 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 9945±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
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| BDBM47876 |
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| n/a |
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| Name | BDBM47876 |
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| Synonyms: | 4-(4-phenylpiperazin-1-yl)carbonyl-1H-quinolin-2-one | 4-(4-phenylpiperazine-1-carbonyl)-1H-quinolin-2-one | 4-(4-phenylpiperazine-1-carbonyl)carbostyril | 4-[oxo-(4-phenyl-1-piperazinyl)methyl]-1H-quinolin-2-one | CVD-0002709 | MAT-POS-916a2c5a-4 | MLS001033759 | SMR000385687 | cid_2083510 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O2 |
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| Mol. Mass. | 333.3838 |
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| SMILES | O=C(N1CCN(CC1)c1ccccc1)c1cc(=O)[nH]c2ccccc12 |
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| Structure | 
|
|---|
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