| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
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| Ligand | BDBM47895 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 9097±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
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| BDBM47895 |
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| n/a |
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| Name | BDBM47895 |
|---|
| Synonyms: | MLS001215963 | N-[5-fluoranyl-1-(2-morpholin-4-ylethyl)-2-oxidanylidene-3H-indol-3-yl]ethanamide;hydrochloride | N-[5-fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydrochloride | N-[5-fluoro-1-[2-(4-morpholinyl)ethyl]-2-oxo-3H-indol-3-yl]acetamide;hydrochloride | N-[5-fluoro-2-keto-1-(2-morpholinoethyl)indolin-3-yl]acetamide;hydrochloride | SMR000544632 | cid_24761173 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20FN3O3 |
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| Mol. Mass. | 321.3467 |
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| SMILES | CC(=O)NC1C(=O)N(CCN2CCOCC2)c2ccc(F)cc12 |
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| Structure | 
|
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