| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3C-like protease |
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| Ligand | BDBM47908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 2299±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
|
|
|
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| BDBM47908 |
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| n/a |
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| Name | BDBM47908 |
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| Synonyms: | 2-chloranyl-1-[3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-2-pyrazolin-1-yl]ethanone | CVD-0002706 | MAT-POS-916a2c5a-1 | MLS001178292 | SMR000591907 | cid_3811656 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17ClN2O3S |
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| Mol. Mass. | 364.846 |
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| SMILES | COc1ccc(cc1OC)C1CC(=NN1C(=O)CCl)c1cccs1 |c:13| |
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| Structure | 
|
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