Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM46563

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM46563

n/a

Name

BDBM46563

Synonyms:

4-chloranyl-N-[1-(phenylmethyl)pyrrolo[3,2-b]quinoxalin-2-yl]benzenesulfonamide | 4-chloro-N-[1-(phenylmethyl)-2-pyrrolo[3,2-b]quinoxalinyl]benzenesulfonamide | MLS000580954 | N-(1-Benzyl-1H-pyrrolo[2,3-b]quinoxalin-2-yl)-4-chloro-benzenesulfonamide | N-(1-benzylpyrrolo[3,2-b]quinoxalin-2-yl)-4-chloro-benzenesulfonamide | N-(1-benzylpyrrolo[3,2-b]quinoxalin-2-yl)-4-chlorobenzenesulfonamide | SMR000220389 | cid_2044030

Type

Small organic molecule

Emp. Form.

C23H17ClN4O2S

Mol. Mass.

448.925

SMILES

Clc1ccc(cc1)S(=O)(=O)Nc1cc2nc3ccccc3nc2n1Cc1ccccc1

Structure