| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Ligand | BDBM75969 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for NR2E3 inverse agonists |
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| IC50 | 1775±n/a nM |
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| Citation |  PubChem, PC Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Name: | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Synonyms: | CTG26 | NCOR2 | NCOR2_HUMAN | Nuclear receptor corepressor 2 (TRAC-1) | nuclear receptor corepressor 2 isoform 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81401.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y618-2 gi_116256445 |
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| Residue: | 766 |
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| Sequence: | MAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLP
TAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVE
HAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKG
IITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV
ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH
HASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLT
HDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPG
VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYL
PPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLL
YRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYN
ISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSS
RKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRL
QAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
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| BDBM75969 |
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| n/a |
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| Name | BDBM75969 |
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| Synonyms: | MLS000536380 | N-(3-chlorophenyl)-4-(3-methyl-4-oxidanylidene-phthalazin-1-yl)benzamide | N-(3-chlorophenyl)-4-(3-methyl-4-oxo-1-phthalazinyl)benzamide | N-(3-chlorophenyl)-4-(3-methyl-4-oxo-3,4-dihydro-1-phthalazinyl)benzamide | N-(3-chlorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide | N-(3-chlorophenyl)-4-(4-keto-3-methyl-phthalazin-1-yl)benzamide | SMR000143417 | cid_1292429 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H16ClN3O2 |
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| Mol. Mass. | 389.834 |
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| SMILES | Cn1nc(-c2ccc(cc2)C(=O)Nc2cccc(Cl)c2)c2ccccc2c1=O |
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| Structure | 
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