Ki Summary

Reaction Details

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Target

RecBCD enzyme subunit RecD

Ligand

BDBM77560

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD

IC50

>118481±n/a nM

Citation

PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

RecBCD enzyme subunit RecD

Name:

RecBCD enzyme subunit RecD

Synonyms:

RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD

Type:

Enzyme Catalytic Domain

Mol. Mass.:

66906.68

Organism:

Escherichia coli str. K-12 substr. MG1655

Description:

gi_16130723

Residue:

608

Sequence:

MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE

BDBM77560

n/a

Name

BDBM77560

Synonyms:

(4-methyl-2-quinolyl)-[(5-nitro-2-furyl)methyleneamino]amine | 4-methyl-N-[(5-nitro-2-furanyl)methylideneamino]-2-quinolinamine | 4-methyl-N-[(5-nitrofuran-2-yl)methylideneamino]quinolin-2-amine | MLS001004347 | SMR000347958 | cid_5014505

Type

Small organic molecule

Emp. Form.

C15H12N4O3

Mol. Mass.

296.2808

SMILES

Cc1cc(N=NCc2ccc(o2)[N+]([O-])=O)nc2ccccc12 |w:4.3|

Structure