| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM64731 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | >118555±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM64731 |
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| n/a |
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| Name | BDBM64731 |
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| Synonyms: | MLS001212827 | N-[[4-(diethylamino)phenyl]-(8-hydroxy-7-quinolinyl)methyl]pentanamide | N-[[4-(diethylamino)phenyl]-(8-hydroxy-7-quinolyl)methyl]valeramide | N-[[4-(diethylamino)phenyl]-(8-hydroxyquinolin-7-yl)methyl]pentanamide | N-[[4-(diethylamino)phenyl]-(8-oxidanylquinolin-7-yl)methyl]pentanamide | Pentanoic acid [(4-diethylamino-phenyl)-(8-hydroxy-quinolin-7-yl)-methyl]-amide | SMR000517138 | cid_2920952 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31N3O2 |
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| Mol. Mass. | 405.5325 |
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| SMILES | CCCCC(=O)NC(c1ccc(cc1)N(CC)CC)c1ccc2cccnc2c1O |
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| Structure | 
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