| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Ligand | BDBM71665 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. |
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| IC50 | 4440±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM23 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Synonyms: | MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23245.32 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285814664 |
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| Residue: | 222 |
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| Sequence: | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHP
LAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQG
LQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIG
AGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
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| BDBM71665 |
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| n/a |
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| Name | BDBM71665 |
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| Synonyms: | 6-chloranyl-2-(5-chloranyl-1-methyl-imidazol-2-yl)-2,3-dihydrochromen-4-one | 6-chloro-2-(5-chloro-1-methyl-2-imidazolyl)-3,4-dihydro-2H-1-benzopyran-4-one | 6-chloro-2-(5-chloro-1-methyl-imidazol-2-yl)chroman-4-one | 6-chloro-2-(5-chloro-1-methylimidazol-2-yl)-2,3-dihydrochromen-4-one | MLS000038396 | SMR000034155 | cid_657803 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10Cl2N2O2 |
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| Mol. Mass. | 297.137 |
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| SMILES | Cn1c(Cl)cnc1C1CC(=O)c2cc(Cl)ccc2O1 |
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| Structure | 
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