| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Ligand | BDBM66036 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. |
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| IC50 | 11200±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM23 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Synonyms: | MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23245.32 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285814664 |
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| Residue: | 222 |
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| Sequence: | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHP
LAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQG
LQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIG
AGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
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| BDBM66036 |
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| n/a |
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| Name | BDBM66036 |
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| Synonyms: | MLS000054763 | N-(2-oxolanylmethyl)-2-(trifluoromethylsulfonyl)-N-[2-(trifluoromethylsulfonyl)ethyl]ethanamine | N-(oxolan-2-ylmethyl)-2-(trifluoromethylsulfonyl)-N-[2-(trifluoromethylsulfonyl)ethyl]ethanamine | SMR000060218 | cid_2998156 | tetrahydrofurfuryl-bis(2-triflylethyl)amine |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17F6NO5S2 |
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| Mol. Mass. | 421.377 |
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| SMILES | FC(F)(F)S(=O)(=O)CCN(CCS(=O)(=O)C(F)(F)F)CC1CCCO1 |
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| Structure | 
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