| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Ligand | BDBM65175 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. |
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| IC50 | 7040±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM23 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Synonyms: | MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23245.32 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285814664 |
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| Residue: | 222 |
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| Sequence: | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHP
LAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQG
LQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIG
AGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
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| BDBM65175 |
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| n/a |
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| Name | BDBM65175 |
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| Synonyms: | 1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluoromethyl)phenyl]thiourea | 1-[(2,4-dichlorophenyl)carbonylamino]-3-[3-(trifluoromethyl)phenyl]thiourea | 1-[[(2,4-dichlorophenyl)-oxomethyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea | MLS000588859 | SMR000212491 | cid_3729816 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10Cl2F3N3OS |
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| Mol. Mass. | 408.226 |
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| SMILES | FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1 |
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| Structure | 
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