| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM65990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 13800±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM65990 |
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| n/a |
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| Name | BDBM65990 |
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| Synonyms: | 3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichlorophenyl)benzamide | MLS000572761 | N-(2,4-dichlorophenyl)-3-(2,5-dioxo-1-pyrrolyl)benzamide | N-(2,4-dichlorophenyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide | N-(2,4-dichlorophenyl)-3-(2,5-dioxopyrrol-1-yl)benzamide | N-(2,4-dichlorophenyl)-3-maleimido-benzamide | SMR000194626 | cid_2275069 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H10Cl2N2O3 |
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| Mol. Mass. | 361.179 |
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| SMILES | Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18| |
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| Structure | 
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