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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Ligand | BDBM42248 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 8150±n/a nM | ||
| Comments | extracted | ||
| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| DNA dC->dU-editing enzyme APOBEC-3G | |||
| Name: | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Synonyms: | ABC3G_HUMAN | APOBEC3G | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46419.54 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_13399304 | ||
| Residue: | 384 | ||
| Sequence: |
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| BDBM42248 | |||
| n/a | |||
| Name | BDBM42248 | ||
| Synonyms: | 9-(3,6-diketocyclohexa-1,4-dien-1-yl)-2-phenethyl-3,6,7,8-tetrahydropyrido[1,2-a]pyrazine-1,4-quinone | 9-(3,6-dioxo-1,4-cyclohexadien-1-yl)-2-(2-phenylethyl)-7,8-dihydro-2H-pyrido[1,2-a]pyrazine-1,4(3H,6H)-dione | 9-(3,6-dioxo-1-cyclohexa-1,4-dienyl)-2-(2-phenylethyl)-3,6,7,8-tetrahydropyrido[1,2-a]pyrazine-1,4-dione | 9-(3,6-dioxocyclohexa-1,4-dien-1-yl)-2-(2-phenylethyl)-3,6,7,8-tetrahydropyrido[1,2-a]pyrazine-1,4-dione | 9-[3,6-bis(oxidanylidene)cyclohexa-1,4-dien-1-yl]-2-(2-phenylethyl)-3,6,7,8-tetrahydropyrido[1,2-a]pyrazine-1,4-dione | MLS000705957 | SMR000226463 | cid_998883 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20N2O4 | ||
| Mol. Mass. | 376.4052 | ||
| SMILES | O=C1CN(CCc2ccccc2)C(=O)C2=C(CCCN12)C1=CC(=O)C=CC1=O |c:27,t:15,23| | ||
| Structure | 
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