Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Ligand | BDBM48851 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 9310±n/a nM | ||
| Comments | extracted | ||
| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| DNA dC->dU-editing enzyme APOBEC-3G | |||
| Name: | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Synonyms: | ABC3G_HUMAN | APOBEC3G | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46419.54 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_13399304 | ||
| Residue: | 384 | ||
| Sequence: |
| ||
| BDBM48851 | |||
| n/a | |||
| Name | BDBM48851 | ||
| Synonyms: | 2-[6-(2-fluorobenzyl)-4-keto-5,7-dimethyl-pyrrolo[3,4-d]pyridazin-3-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-(2-fluorobenzyl)-5,7-dimethyl-1-oxo-1,6-dihydro-2H-pyrrolo[3,4-d]pyridazin-2-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxidanylidene-pyrrolo[3,4-d]pyridazin-3-yl]-N-[2,3,5,6-tetrakis(fluoranyl)phenyl]ethanamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxo-3-pyrrolo[3,4-d]pyridazinyl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxopyrrolo[3,4-d]pyridazin-3-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | MLS000660595 | SMR000310114 | cid_16194171 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H17F5N4O2 | ||
| Mol. Mass. | 476.3987 | ||
| SMILES | Cc1n(Cc2ccccc2F)c(C)c2c1cnn(CC(=O)Nc1c(F)c(F)cc(F)c1F)c2=O | ||
| Structure | 
| ||