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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase JAK2 | ||
| Ligand | BDBM270864 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | JAK Enzyme Assay | ||
| IC50 | >10000±n/a nM | ||
| Citation |  Gauvry, N; Tahtaoui, C; Furet, P; Ducray, P Compounds US Patent US10059709 Publication Date 8/28/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase JAK2 | |||
| Name: | Tyrosine-protein kinase JAK2 | ||
| Synonyms: | JAK-2 | JAK2 | JAK2_HUMAN | Janus kinase 2 | Janus kinase 2 (JAK2) | Janus kinase 2 (a protein tyrosine kinase) | ||
| Type: | Protein | ||
| Mol. Mass.: | 130684.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60674 | ||
| Residue: | 1132 | ||
| Sequence: |
| ||
| BDBM270864 | |||
| n/a | |||
| Name | BDBM270864 | ||
| Synonyms: | US10059709, 10 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C13H22ClN5O2S | ||
| Mol. Mass. | 347.864 | ||
| SMILES | CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1cc(Cl)nc(N)n1 |r,wU:9.12,wD:6.5,(6,2.8,;4.67,2.03,;3.33,2.8,;4.1,4.13,;2.56,1.46,;2,3.57,;.67,2.8,;-.67,3.57,;-2,2.8,;-2,1.26,;-.67,.49,;.67,1.26,;-3.33,.49,;-4.67,1.26,;-3.33,-1.05,;-4.67,-1.82,;-4.67,-3.36,;-6,-4.13,;-3.33,-4.13,;-2,-3.36,;-.67,-4.13,;-2,-1.82,)| | ||
| Structure | 
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