| Reaction Details |
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 | Report a problem with these data |
| Target | Putative farnesyl pyrophosphate synthase |
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| Ligand | BDBM81349 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| pH | 7.7±0 |
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| Temperature | 310.15±0 K |
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| Ki | 1.60±0.26 nM |
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| IC50 | 52.7±7.6 nM |
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| Citation |  Artz, JD; Dunford, JE; Arrowood, MJ; Dong, A; Chruszcz, M; Kavanagh, KL; Minor, W; Russell, RG; Ebetino, FH; Oppermann, U; Hui, R Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis. Chem Biol15:1296-306 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Putative farnesyl pyrophosphate synthase |
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| Name: | Putative farnesyl pyrophosphate synthase |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 44960.82 |
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| Organism: | Cryptosporidium parvum |
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| Description: | Belongs to the FPP/GGPP synthase family. Q5CR09 |
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| Residue: | 384 |
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| Sequence: | ILFHLLKITFIDSIFFALHDNYLTPQFIFNKMNDLQIEYDYTDFINYYDKFKVIVYNVLK
KLPLNDEIRKPVIEYYLNCIDYNVKKGKHIRGKILVLISSLSSAYSNIKRDSIYLLGWVV
EAIQALILIADDIMDSGKFRRGAPCWYIVHGQSNAINDIFFLKMLSLSLIFELSSVFGND
IVMKIQKIYNESIFFTVLGQHLDLSYFDLSKADKISERYFSMVEMKTSRYTFYMPVFFGL
TLSEIQVSSAQLNLIEAILYKLGEFYQVHNDVSDYLFNDSNADDICRFKLTWPLQKSFEI
ADEEMKLKISENYGKNSSLVKDCYNLLKINEHYLEYQRNALDYLIKLVKDITDDSLQKVF
IHLIHQISELITNSRSNADSNNSL
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| BDBM81349 |
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| n/a |
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| Name | BDBM81349 |
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| Synonyms: | IBAN |
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| Type | Small organic molecule |
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| Emp. Form. | C10H25NO7P2 |
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| Mol. Mass. | 333.2555 |
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| SMILES | CCCCCN(C)CCCC(O)(P(O)(O)=O)P(O)(O)=O |
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| Structure | 
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