| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H1 receptor |
|---|
| Ligand | BDBM81470 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 2.3±n/a nM |
|---|
| Comments | PDSP_1217 |
|---|
| Citation |  Tran, VT; Chang, RS; Snyder, SH Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine. Proc Natl Acad Sci U S A75:6290-4 (1978) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Histamine H1 receptor |
|---|
| Name: | Histamine H1 receptor |
|---|
| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 55716.35 |
|---|
| Organism: | RAT |
|---|
| Description: | HISTAMINE H1 HRH1 RAT::P31390 |
|---|
| Residue: | 486 |
|---|
| Sequence: | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKC
ETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLR
SDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCF
RLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTT
DSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIM
AAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKK
ILHIRS
|
|
|
|---|
| BDBM81470 |
|---|
| n/a |
|---|
| Name | BDBM81470 |
|---|
| Synonyms: | CAS_14677 | Methdilazine | NSC_14677 | US9504692, 3943 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2S |
|---|
| Mol. Mass. | 296.43 |
|---|
| SMILES | CN1CCC(CN2c3ccccc3Sc3ccccc23)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
