| Reaction Details |
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 | Report a problem with these data |
| Target | HTH-type transcriptional regulator MgrA |
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| Ligand | BDBM81555 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| pH | 7.4±0 |
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| Temperature | 276.65±0 K |
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| IC50 | 3.2e+4±n/a nM |
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| Citation |  Sun, F; Zhou, L; Zhao, BC; Deng, X; Cho, H; Yi, C; Jian, X; Song, CX; Luan, CH; Bae, T; Li, Z; He, C Targeting MgrA-Mediated Virulence Regulation in Staphylococcus aureus. Chem Biol18:1032-41 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| HTH-type transcriptional regulator MgrA |
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| Name: | HTH-type transcriptional regulator MgrA |
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| Synonyms: | HTH-type transcriptional regulator mgrA (MgrA) | MGRA_STAAU | Regulator of autolytic activity | mgr | mgrA |
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| Type: | Protein |
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| Mol. Mass.: | 17090.77 |
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| Organism: | Staphylococcus aureus |
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| Description: | P0C1S0 |
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| Residue: | 147 |
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| Sequence: | MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVT
ELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSETIRPELSNASDKVASAS
SLSQDEVKELNRLLGKVIHAFDETKEK
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| BDBM81555 |
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| n/a |
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| Name | BDBM81555 |
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| Synonyms: | MgrA inhibitor, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15NO2S |
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| Mol. Mass. | 249.329 |
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| SMILES | Cc1ccc(C)n1[C@@H](CC(O)=O)c1ccsc1 |r| |
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| Structure | 
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