| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM81679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 0.28±0.0 nM |
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| Citation |  Chellappan, S; Kiran Kumar Reddy, GS; Ali, A; Nalam, MN; Anjum, SG; Cao, H; Kairys, V; Fernandes, MX; Altman, MD; Tidor, B; Rana, TM; Schiffer, CA; Gilson, MK Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des69:298-313 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 10653.94 |
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| Organism: | Human immunodeficiency virus |
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| Description: | O90783 |
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| Residue: | 98 |
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| Sequence: | PQVTLWQRPLVTIRVGGQLKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD
QITVEICGHKAIGTVLVGPTPVNIIGRNLLTIGCTLNF
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| BDBM81679 |
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| n/a |
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| Name | BDBM81679 |
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| Synonyms: | NFV |
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| Type | Small organic molecule |
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| Emp. Form. | C32H45N3O4S |
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| Mol. Mass. | 567.782 |
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| SMILES | Cc1c(O)cccc1C(=O)N[C@H](CSc1ccccc1)[C@H](O)CN1CC2CCCCC2C[C@H]1C(=O)NC(C)(C)C |r| |
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| Structure | 
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