| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
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| Ligand | BDBM50020192 |
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| Substrate/Competitor | n/a |
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| Ki | 0.67±n/a nM |
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| Comments | PDSP_1743 |
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| Citation |  Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J Pharmacol Exp Ther259:323-9 (1991) [PubMed] |
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| More Info.: | Get all data from this article |
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| Alpha-2C adrenergic receptor |
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| Name: | Alpha-2C adrenergic receptor |
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| Synonyms: | ADA2C_DIDVI | ADRA2C | Alpha-2C adrenergic receptor | adrenergic Alpha2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 53254.77 |
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| Organism: | OPOSSUM |
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| Description: | adrenergic Alpha2C ADRA2C OPOSSUM::P35405 |
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| Residue: | 469 |
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| Sequence: | MDLQLTTNSTDSGDRGGSSNESLQRQPPSQYSPAEVAGLAAVVSFLIVFTIVGNVLVVIA
VLTSRALKAPQNLFQVSLASADILVATLVMPFSLANELMNYWYFGKVWCVIYLALDVLFC
TSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRIKGIIVTVWLISAVISFPPLISLYRDPE
DDLYPQCELNDETWYILSSCIGSFFAPCIIMVLVYVRIYRVAKLRTRTLSEKRTVPEGSS
QTENGLSRPPVGAGPSTAAAAAASLRLQAGENGHYHLHHHHHHLHHHHHHHHHQLRKSAE
LEDIELEESSTSENRRRRRSREEAAARKGSRGFSFSFSSTKGGQSAGAGSRLSRASNRSL
EFFSTHRRRKRSSLCRRKVTQAREKRFTFVLAVVMGVFVVCWFPFFFTYSLYGICREACQ
VPETLFKFFFWIGYCNSSLNPVIYTIFNQDFRRSFKHILFKKKKKTSLQ
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| BDBM50020192 |
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| n/a |
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| Name | BDBM50020192 |
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| Synonyms: | 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL300555 | Spiroxatrine |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25N3O3 |
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| Mol. Mass. | 379.4522 |
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| SMILES | O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1 |
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| Structure | 
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