Reaction Details |
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Target | Alpha-2C adrenergic receptor |
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Ligand | BDBM50020192 |
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Substrate/Competitor | n/a |
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Ki | 0.59±n/a nM |
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Comments | PDSP_1743 |
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Citation | Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J Pharmacol Exp Ther259:323-9 (1991) [PubMed] |
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More Info.: | Get all data from this article |
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Alpha-2C adrenergic receptor |
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Name: | Alpha-2C adrenergic receptor |
Synonyms: | ADRA2C | adrenergic Alpha2C |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 27257.01 |
Organism: | OK |
Description: | adrenergic Alpha2C ADRA2C OK::G3GWB4 |
Residue: | 230 |
Sequence: | MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIV
AVWLISAVISFPPLVSFYRRSDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARI
YRFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREAC
QLPEPLFKFFFWIGYCKSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
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BDBM50020192 |
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n/a |
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Name | BDBM50020192 |
Synonyms: | 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL300555 | Spiroxatrine |
Type | Small organic molecule |
Emp. Form. | C22H25N3O3 |
Mol. Mass. | 379.4522 |
SMILES | O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1 |
Structure |
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