| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50035057 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_779 |
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| Citation |  Schipper, J; Tulp, MT; Sijbesma, H Neurochemical profile of eltoprazine. Drug Metabol Drug Interact8:85-114 (1990) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50035057 |
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| n/a |
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| Name | BDBM50035057 |
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| Synonyms: | (eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | 1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | CHEMBL282614 | Eltoprazine |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16N2O2 |
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| Mol. Mass. | 220.2676 |
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| SMILES | C1CN(CCN1)c1cccc2OCCOc12 |
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| Structure | 
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