| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
|---|
| Ligand | BDBM35256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 40±n/a nM |
|---|
| Comments | PDSP_1235 |
|---|
| Citation |  Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Sodium-dependent isomerization of dopamine D-2 receptors characterized using [125I]epidepride, a high-affinity substituted benzamide ligand. J Pharmacol Exp Ther252:1108-16 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2C adrenergic receptor |
|---|
| Name: | Alpha-2C adrenergic receptor |
|---|
| Synonyms: | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | Alpha-2C adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2C |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49890.50 |
|---|
| Organism: | RAT |
|---|
| Description: | adrenergic Alpha2 0 RAT::P22086 |
|---|
| Residue: | 458 |
|---|
| Sequence: | MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRR
GGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRAR
SSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFW
IGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
|
|
|
|---|
| BDBM35256 |
|---|
| n/a |
|---|
| Name | BDBM35256 |
|---|
| Synonyms: | (S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+) | MIANSERIN (-) | Tolvon |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2 |
|---|
| Mol. Mass. | 264.3648 |
|---|
| SMILES | [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
