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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Leucyl-cystinyl aminopeptidase | ||
| Ligand | BDBM271288 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition of Human P-LAP (hP-LAP) Assay | ||
| IC50 | 1.40±n/a nM | ||
| Citation |  Kawaguchi, K; Ishihata, A; Inagaki, Y; Tsuchiya, K; Hanadate, T; Kanai, A; Kaizawa, H; Kazami, J; Morikawa, H; Hiramoto, M; Enjo, K; Takamatsu, H Pyridine derivative US Patent US10059720 Publication Date 8/28/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Leucyl-cystinyl aminopeptidase | |||
| Name: | Leucyl-cystinyl aminopeptidase | ||
| Synonyms: | Aminopeptidase | Aminopeptidase (P-LAP) | Cystinyl aminopeptidase | IRAP | Insulin-regulated membrane aminopeptidase | Insulin-responsive aminopeptidase | LCAP_HUMAN | LNPEP | Leucyl-cystinyl aminopeptidase, pregnancy serum form | OTASE | Oxytocinase | P-LAP | Placental leucine aminopeptidase | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 117334.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1473494 | ||
| Residue: | 1025 | ||
| Sequence: |
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| BDBM271288 | |||
| n/a | |||
| Name | BDBM271288 | ||
| Synonyms: | US10059720, Example 103 | US10975091, Example 103 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H28N2O4S | ||
| Mol. Mass. | 368.491 | ||
| SMILES | CSC[C@H](N)[C@](O)(Cc1cc(O[C@H]2CC[C@H](C)CC2)ccn1)C(O)=O |r,wU:5.6,3.3,15.15,wD:12.11,5.5,(-7.34,-2.31,;-6,-3.08,;-4.67,-2.31,;-3.33,-3.08,;-3.33,-4.62,;-2,-2.31,;-1.23,-.98,;-.67,-3.08,;.67,-2.31,;.67,-.77,;2,,;2,1.54,;3.33,2.31,;4.67,1.54,;6,2.31,;6,3.85,;7.34,4.62,;4.67,4.62,;3.33,3.85,;3.33,-.77,;3.33,-2.31,;2,-3.08,;-2.77,-.98,;-4.26,-1.37,;-2,.36,)| | ||
| Structure | 
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