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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Leucyl-cystinyl aminopeptidase | ||
| Ligand | BDBM271310 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition of IRAP Assay | ||
| IC50 | 0.900±n/a nM | ||
| Citation |  Kawaguchi, K; Ishihata, A; Inagaki, Y; Tsuchiya, K; Hanadate, T; Kanai, A; Kaizawa, H; Kazami, J; Morikawa, H; Hiramoto, M; Enjo, K; Takamatsu, H Pyridine derivative US Patent US10059720 Publication Date 8/28/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Leucyl-cystinyl aminopeptidase | |||
| Name: | Leucyl-cystinyl aminopeptidase | ||
| Synonyms: | Cystinyl aminopeptidase | GP160 | Insulin-regulated membrane aminopeptidase | Insulin-responsive aminopeptidase | Irap | LCAP_RAT | Leucyl-cystinyl aminopeptidase | Lnpep | Otase | Oxytocinase | P-LAP | Placental leucine aminopeptidase | Vesicle protein of 165 kDa | Vp165 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 117179.39 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_98523 | ||
| Residue: | 1025 | ||
| Sequence: |
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| BDBM271310 | |||
| n/a | |||
| Name | BDBM271310 | ||
| Synonyms: | US10059720, Example 125 | US10975091, Example 125 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H31FN2O4 | ||
| Mol. Mass. | 382.4695 | ||
| SMILES | C[C@H]1CC[C@@H](CC1)Oc1ccnc(C[C@@](O)([C@@H](N)CC(C)(C)F)C(O)=O)c1 |r,wU:14.14,16.17,1.0,wD:4.7,14.15,(7.34,4.62,;6,3.85,;6,2.31,;4.67,1.54,;3.33,2.31,;3.33,3.85,;4.67,4.62,;2,1.54,;2,,;3.33,-.77,;3.33,-2.31,;2,-3.08,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;-1.23,-.98,;-3.33,-3.08,;-3.33,-4.62,;-4.67,-2.31,;-6,-3.08,;-7.34,-2.31,;-6,-4.62,;-7.34,-3.85,;-2.77,-.98,;-2,.36,;-4.26,-1.37,;.67,-.77,)| | ||
| Structure | 
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