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Target5-hydroxytryptamine receptor 5A
LigandBDBM35234
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_1348
Citation Erlander, MGLovenberg, TWBaron, BMde Lecea, LDanielson, PERacke, MSlone, ALSiegel, BWFoye, PECannon, K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A90:3452-6 (1993) [PubMed]  Article
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5-hydroxytryptamine receptor 5A
Name:5-hydroxytryptamine receptor 5A
Synonyms:5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_RAT | 5ht5a | Htr5a | REC17 | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:Enzyme Catalytic Domain
Mol. Mass.:40684.21
Organism:RAT
Description:5-HT5a HTR5A RAT::P35364
Residue:357
Sequence:
MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFG
WGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVS
PIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
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BDBM35234
n/a
NameBDBM35234
Synonyms:DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradrenaline,(+) | [3H]NE
Typeradiolabeled ligand
Emp. Form.C8H11NO3
Mol. Mass.169.1778
SMILESNCC(O)c1ccc(O)c(O)c1
Structure
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