| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
|---|
| Ligand | BDBM50130257 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 3±n/a nM |
|---|
| Comments | PDSP_515 |
|---|
| Citation |  Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther268:1403-10 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 6 |
|---|
| Name: | 5-hydroxytryptamine receptor 6 |
|---|
| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_RAT | Htr6 | ST-B17 | Serotonin (5-HT) receptor | Serotonin 6 (5-HT6) receptor | Serotonin receptor 6 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46945.51 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT6 HTR6 RAT::P31388 |
|---|
| Residue: | 436 |
|---|
| Sequence: | MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQC
RLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVP
RTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVP
DQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLS
QTLWSLRYGRIHSVPP
|
|
|
|---|
| BDBM50130257 |
|---|
| n/a |
|---|
| Name | BDBM50130257 |
|---|
| Synonyms: | (3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine | (E)-chlorprothixene | CHEMBL90125 | CHLORPROTHIXENE | Chlorprothixene (cis) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18ClNS |
|---|
| Mol. Mass. | 315.86 |
|---|
| SMILES | CN(C)CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
