| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM83217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | 2366±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM83217 |
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| n/a |
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| Name | BDBM83217 |
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| Synonyms: | 4-[4-(6,8-dibromo-2-quinolinyl)phenyl]morpholine | 4-[4-(6,8-dibromo-2-quinolyl)phenyl]morpholine | 4-[4-(6,8-dibromoquinolin-2-yl)phenyl]morpholine | 4-[4-[6,8-bis(bromanyl)quinolin-2-yl]phenyl]morpholine | 6,8-dibromo-2-(4-morpholinophenyl)quinoline | MLS000547366 | SMR000180265 | cid_1472977 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16Br2N2O |
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| Mol. Mass. | 448.151 |
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| SMILES | Brc1cc(Br)c2nc(ccc2c1)-c1ccc(cc1)N1CCOCC1 |
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| Structure | 
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