| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM63144 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | 3698±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM63144 |
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| n/a |
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| Name | BDBM63144 |
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| Synonyms: | 3-amino-6-phenyl-2-thieno[2,3-b]pyridinecarboxylic acid propan-2-yl ester | 3-amino-6-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid isopropyl ester | MLS000581763 | SMR000200288 | cid_2215233 | isopropyl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate | propan-2-yl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate | propan-2-yl 3-azanyl-6-phenyl-thieno[2,3-b]pyridine-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N2O2S |
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| Mol. Mass. | 312.386 |
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| SMILES | CC(C)OC(=O)c1sc2nc(ccc2c1N)-c1ccccc1 |
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| Structure | 
|
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