Reaction Details |
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Target | Beta-lactamase |
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Ligand | BDBM50229 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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IC50 | 4440±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Beta-lactamase |
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Name: | Beta-lactamase |
Synonyms: | Beta lactamase |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 31513.38 |
Organism: | Pseudomonas aeruginosa |
Description: | gi_114881106 |
Residue: | 286 |
Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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BDBM50229 |
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n/a |
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Name | BDBM50229 |
Synonyms: | MLS000574746 | SMR000196176 | [3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(4-methoxyphenyl)methanone | [3-amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl](4-methoxyphenyl)methanone | [3-amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone | [3-azanyl-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone | cid_1190955 |
Type | Small organic molecule |
Emp. Form. | C22H18N2O3S |
Mol. Mass. | 390.455 |
SMILES | COc1ccc(cc1)C(=O)c1sc2nc(ccc2c1N)-c1ccc(OC)cc1 |
Structure |
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