| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM54811 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | >49712±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
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| BDBM54811 |
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| n/a |
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| Name | BDBM54811 |
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| Synonyms: | 7-chloranyl-3-phenyl-[1,3]thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl-2-thiazolo[4,5-d]pyrimidinethione | 7-chloro-3-phenyl-[1,3]thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl-thiazolo[4,5-d]pyrimidine-2-thione | 7-chloro-3-phenyl[1,3]thiazolo[4,5-d]pyrimidine-2(3H)-thione | MLS000727642 | SMR000306339 | cid_373692 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H6ClN3S2 |
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| Mol. Mass. | 279.768 |
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| SMILES | Clc1ncnc2n(-c3ccccc3)c(=S)sc12 |
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| Structure | 
|
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