| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM67298 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | 4369±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
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| BDBM67298 |
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| n/a |
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| Name | BDBM67298 |
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| Synonyms: | MLS000777130 | N-[(5E)-5-(2-hydroxy-5-nitro-benzylidene)-4-keto-2-thiazolin-2-yl]-1-phenyl-methanesulfonamide | N-[(5E)-5-[(2-hydroxy-5-nitrophenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]-1-phenylmethanesulfonamide | N-[(5E)-5-[(2-hydroxy-5-nitrophenyl)methylidene]-4-oxo-2-thiazolyl]-1-phenylmethanesulfonamide | N-[(5E)-5-[(5-nitro-2-oxidanyl-phenyl)methylidene]-4-oxidanylidene-1,3-thiazol-2-yl]-1-phenyl-methanesulfonamide | N-[5-[1-(2-Hydroxy-5-nitro-phenyl)-meth-(E)-ylidene]-4-oxo-thiazolidin-(2E)-ylidene]-C-phenyl-methanes ulfonamide | SMR000413526 | cid_1893759 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O6S2 |
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| Mol. Mass. | 419.432 |
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| SMILES | Oc1ccc(cc1\C=C1\SC(NS(=O)(=O)Cc2ccccc2)=NC1=O)[N+]([O-])=O |c:23| |
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| Structure | 
|
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