Reaction Details |
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Target | Beta-lactamase |
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Ligand | BDBM31372 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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IC50 | 2639±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Beta-lactamase |
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Name: | Beta-lactamase |
Synonyms: | Beta lactamase |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 31513.38 |
Organism: | Pseudomonas aeruginosa |
Description: | gi_114881106 |
Residue: | 286 |
Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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BDBM31372 |
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n/a |
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Name | BDBM31372 |
Synonyms: | 3-(2-furanyl)-5-(4-nitrophenyl)-2-phenyl-3,4-dihydropyrazole | 3-(furan-2-yl)-5-(4-nitrophenyl)-2-phenyl-3,4-dihydropyrazole | 5-(2-furyl)-3-(4-nitrophenyl)-1-phenyl-2-pyrazoline | 5-(2-furyl)-3-(4-nitrophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole | MLS000861141 | SMR000459925 | cid_564008 |
Type | Small organic molecule |
Emp. Form. | C19H15N3O3 |
Mol. Mass. | 333.3407 |
SMILES | [O-][N+](=O)c1ccc(cc1)C1=NN(C(C1)c1ccco1)c1ccccc1 |t:10| |
Structure |
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