| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM83251 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | 3598±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM83251 |
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| n/a |
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| Name | BDBM83251 |
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| Synonyms: | 6-[2-(4-aminophenyl)ethynyl]-2,3-dimethoxy-9-xanthenone | 6-[2-(4-aminophenyl)ethynyl]-2,3-dimethoxy-xanthen-9-one | 6-[2-(4-aminophenyl)ethynyl]-2,3-dimethoxy-xanthone | 6-[2-(4-aminophenyl)ethynyl]-2,3-dimethoxyxanthen-9-one | MLS001144048 | SMR000526304 | cid_24747933 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17NO4 |
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| Mol. Mass. | 371.3854 |
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| SMILES | COc1cc2oc3cc(ccc3c(=O)c2cc1OC)C#Cc1ccc(N)cc1 |
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| Structure | 
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