| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM83273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
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| IC50 | 2744±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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|
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| BDBM83273 |
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| n/a |
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| Name | BDBM83273 |
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| Synonyms: | 2-[2-[(Z)-indol-3-ylidenemethyl]hydrazinyl]-N-(2-methoxyphenyl)-5-nitro-benzenesulfonamide | 2-[2-[(Z)-indol-3-ylidenemethyl]hydrazinyl]-N-(2-methoxyphenyl)-5-nitrobenzenesulfonamide | 2-[N'-[(Z)-indol-3-ylidenemethyl]hydrazino]-N-(2-methoxyphenyl)-5-nitro-benzenesulfonamide | 2-[[(Z)-3-indolylidenemethyl]hydrazo]-N-(2-methoxyphenyl)-5-nitrobenzenesulfonamide | MLS002637164 | SMR000155381 | cid_6514766 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19N5O5S |
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| Mol. Mass. | 465.482 |
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| SMILES | COc1ccccc1NS(=O)(=O)c1cc(ccc1N=[NH+]Cc1c[n-]c2ccccc12)[N+]([O-])=O |w:18.19| |
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| Structure | 
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