Reaction Details | |||
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Target | Orotidine 5'-phosphate decarboxylase | ||
Ligand | BDBM83831 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter | ||
EC50 | >59630±n/a nM | ||
Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] | ||
More Info.: | Get all data from this article, Assay Method | ||
Orotidine 5'-phosphate decarboxylase | |||
Name: | Orotidine 5'-phosphate decarboxylase | ||
Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 30195.13 | ||
Organism: | Aspergillus niger | ||
Description: | gi_2395 | ||
Residue: | 277 | ||
Sequence: |
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BDBM83831 | |||
n/a | |||
Name | BDBM83831 | ||
Synonyms: | (1S,3R,3aS,6aR)-3-ethyl-1-[[ethyl-(4-methoxyphenyl)sulfonylamino]methyl]-4,6-dioxo-5-(phenylmethyl)-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid | (1S,3R,3aS,6aR)-5-benzyl-3-ethyl-1-[[ethyl-(4-methoxyphenyl)sulfonyl-amino]methyl]-4,6-diketo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid | MLS002477025 | SMR001398948 | cid_44246827 | methyl (1S,3R,3aS,6aR)-3-ethyl-1-[[ethyl-(4-methoxyphenyl)sulfonyl-amino]methyl]-4,6-bis(oxidanylidene)-5-(phenylmethyl)-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate;2,2,2-tris(fluoranyl)ethanoic acid | methyl (1S,3R,3aS,6aR)-5-benzyl-3-ethyl-1-[[ethyl-(4-methoxyphenyl)sulfonylamino]methyl]-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate;2,2,2-trifluoroacetic acid | ||
Type | Small organic molecule | ||
Emp. Form. | C27H33N3O7S | ||
Mol. Mass. | 543.632 | ||
SMILES | CCN(C[C@H]1N[C@](CC)([C@@H]2[C@H]1C(=O)N(Cc1ccccc1)C2=O)C(=O)OC)S(=O)(=O)c1ccc(OC)cc1 | ||
Structure |