Reaction Details | |||
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Target | Orotidine 5'-phosphate decarboxylase | ||
Ligand | BDBM83833 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter | ||
EC50 | >59644±n/a nM | ||
Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] | ||
More Info.: | Get all data from this article, Assay Method | ||
Orotidine 5'-phosphate decarboxylase | |||
Name: | Orotidine 5'-phosphate decarboxylase | ||
Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 30195.13 | ||
Organism: | Aspergillus niger | ||
Description: | gi_2395 | ||
Residue: | 277 | ||
Sequence: |
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BDBM83833 | |||
n/a | |||
Name | BDBM83833 | ||
Synonyms: | MLS002608893 | N-(1-adamantylmethyl)-2-[(1S,12bS)-12b-ethyl-1-[4-(2-furoyl)piperazine-1-carbonyl]-4-keto-9-methoxy-1,2,3,6,7,12-hexahydropyrido[2,1-a]-carbolin-3-yl]acetamide | N-(1-adamantylmethyl)-2-[(1S,12bS)-12b-ethyl-1-[4-(furan-2-carbonyl)piperazine-1-carbonyl]-9-methoxy-4-oxo-1,2,3,6,7,12-hexahydroindolo[2,3-a]quinolizin-3-yl]acetamide | N-(1-adamantylmethyl)-2-[(1S,12bS)-12b-ethyl-1-[4-(furan-2-ylcarbonyl)piperazin-1-yl]carbonyl-9-methoxy-4-oxidanylidene-1,2,3,6,7,12-hexahydroindolo[2,3-a]quinolizin-3-yl]ethanamide | N-(1-adamantylmethyl)-2-[(1S,12bS)-12b-ethyl-1-[[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-oxomethyl]-9-methoxy-4-oxo-1,2,3,6,7,12-hexahydroindolo[2,3-a]quinolizin-3-yl]acetamide | SMR001530122 | cid_44601827 | ||
Type | Small organic molecule | ||
Emp. Form. | C41H51N5O6 | ||
Mol. Mass. | 709.8735 | ||
SMILES | [H]C12CC3([H])CC([H])(C1)CC(CNC(=O)CC1C[C@H](C(=O)N4CCN(CC4)C(=O)c4ccco4)[C@]4(CC)N(CCc5c4[nH]c4ccc(OC)cc54)C1=O)(C2)C3 |TLB:5:3:53:6.9.8,THB:2:3:9:1.53.8,2:1:9:3.54.5| | ||
Structure |