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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orotidine 5'-phosphate decarboxylase | ||
| Ligand | BDBM83834 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter | ||
| EC50 | >59597±n/a nM | ||
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orotidine 5'-phosphate decarboxylase | |||
| Name: | Orotidine 5'-phosphate decarboxylase | ||
| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 30195.13 | ||
| Organism: | Aspergillus niger | ||
| Description: | gi_2395 | ||
| Residue: | 277 | ||
| Sequence: |
| ||
| BDBM83834 | |||
| n/a | |||
| Name | BDBM83834 | ||
| Synonyms: | (5R,5aS,8aR,8bS)-5-ethyl-3-[(4-methoxycarbonylphenyl)methylthio]-6,8-dioxo-7-(phenylmethyl)-1,5a,8a,8b-tetrahydropyrrolo[1,2]pyrrolo[3,5-c]imidazole-5-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid | (5R,5aS,8aR,8bS)-7-benzyl-3-[(4-carbomethoxybenzyl)thio]-5-ethyl-6,8-diketo-1,5a,8a,8b-tetrahydropyrrolo[1,2]pyrrol[3,5-c]imidazole-5-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid | MLS002643078 | SMR001551461 | cid_44602247 | methyl (5R,5aS,8aR,8bS)-5-ethyl-3-[(4-methoxycarbonylphenyl)methylsulfanyl]-6,8-bis(oxidanylidene)-7-(phenylmethyl)-1,5a,8a,8b-tetrahydropyrrolo[1,2]pyrrolo[3,5-c]imidazole-5-carboxylate;2,2,2-tris(fluoranyl)ethanoic acid | methyl (5R,5aS,8aR,8bS)-7-benzyl-5-ethyl-3-[(4-methoxycarbonylphenyl)methylsulfanyl]-6,8-dioxo-1,5a,8a,8b-tetrahydropyrrolo[1,2]pyrrolo[3,5-c]imidazole-5-carboxylate;2,2,2-trifluoroacetic acid | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H29N3O6S | ||
| Mol. Mass. | 535.611 | ||
| SMILES | CC[C@@]1([C@@H]2[C@H]([C@H]3CN=C(SCc4ccc(cc4)C(=O)OC)N13)C(=O)N(Cc1ccccc1)C2=O)C(=O)OC |t:7| | ||
| Structure | 
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