| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50009525 |
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| Substrate/Competitor | n/a |
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| Ki | 6918.3±n/a nM |
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| Comments | PDSP_62 |
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| Citation |  Barrett, RJ; May, JM; Martin, PL; Miller, JR In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist. J Pharmacol Exp Ther265:227-36 (1993) [PubMed] |
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| More Info.: | Get all data from this article |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_BOVIN | ADENOSINE A2 | ADORA2B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36398.35 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE A2 0 BOVINE::Q1LZD0 |
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| Residue: | 332 |
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| Sequence: | MPLEAQDAVYVALELALAALSVTGNVLVCAAVGTSSALQTPTNYFLVSLAAADVAVGLFA
IPFAVTISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAVRVPLRYKSLVTGA
RARGVIAALWVLAFGIGLTPFLGWNDRKIATNCTEPGDAATNVSCCLIRCLFENVVPMSY
MVYFNFFGCVLPPLLIMLVIYVKIFLVACRQLQRTELMDHSRTVLQREIHAAKSLALIVG
IFALCWLPVHTINCASLFQPTWAKVKPKWAINTAILLSHANSAVNPIVYAYRNRDFRYTF
HKIISRYILCRTHILKSGEGQVGSQPTLQLGL
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| BDBM50009525 |
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| n/a |
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| Name | BDBM50009525 |
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| Synonyms: | 2-CI Adenosine | 2-Chloroadenosine | 2-Chloroado | 2-[6-Amino-2-(2-cyclopentyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL285819 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12ClN5O4 |
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| Mol. Mass. | 301.686 |
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| SMILES | Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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